Horizon Scanning

During the horizon scanning process, scientific publications are screened and evaluated to identify and analyze possible environmental effects of new technical developments and their applications in the field of genetic engineering/biotechnology considering the precautionary principle. The results of the horizon scanning are made available to the public in form of short summaries. It is an ongoing collection of current literature that does not claim to be complete and is continuously updated.
The current focus of the horizon scanning process can be found → here and a glossary with explanations of the most important terms can be found  here

Detection of CRISPR-mediated genome modifications through altered methylation patterns of CpG islands.

Background – epigenetics The field of epigenetics deals with hereditary changes that do not change the DNA sequence itself. Epigenetic markers determine which genes are activated or silenced in certains cells and tissues, so they influence gene expression. Thus, the basic structure of the DNA remains unchanged. Epigenetic markers are biochemical appendages of DNA. Epigenetics […]

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Exosome-mediated horizontal gene transfer occurs in double-strand break repair during genome editing.

Double-strand breaks (DSBs) in DNA occur naturally in every organism (microoorganisms, plants, animals, humans) and are mended by the cell’s own repair mechanisms. The original state before the DNA damage can be restored or the genome can be changed at that particular region, i.e. the introduction of small insertions, deletions or point mutations. In addition […]

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A Real-Time Quantitative PCR Method Specific for Detection and Quantification of the First Commercialized Genome-Edited Plant.

The authors of this study succeeded in designing a specific PCR method to detect a Cibus rapeseed variety that carries a herbicide tolerance in its genome. An important prerequisite for the application of the method must be fulfilled: the changes in the respective gene location of the examined varieties must be known beforehand. First, the […]

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