De novo domestication of wild tomato using genome editing

In this study, CRISPR/Cas9 was used to alter six genes in a wild tomato species that were found to be important for the yield and nutritional content of domesticated tomatoes. Six genes of the wild tomatoes were changed which resulted in an alteration of their shape, size, the number of fruits and the nutrient content. These genome-edited, „de novo domesticated“ tomatoes have properties like increased stress tolerance and disease resistance that have been lost during the course of traditional plant breeding.